Intra-Uterine Insemination

What is IUI?

Intra-Uterine Insemination (also known as artificial insemination) is the process of preparing and delivering sperms so that a highly concentrated amount of active motile normal sperms is placed directly through the cervix into the uterus. The current IUI pregnancy rate per treatment is 10-15%. IUI can be performed with fertility drugs for the female patient. Compared to timed intercourse, it is generally accepted that there is a 2-fold higher pregnancy rate with IUI. Thus, for infertility patients, IUI is commonly performed as a low-tech, cost-effective approach to enhancing fertility in patients.

Cases which can be used IUI :

  1. When the husband is impotent.
  2. The scarcity of sperm or moderate motility.
  3. In case of vaginismus.
  4. Immunological factor.
  5. When the wife has infections in the vagina or cervix.

Cases that do not fit with IUI:

  1. Death of sperm in semen.
  2. Count of sperm is less than five million / ml.
  3. When the husband can do ejaculation.

Who is IUI suitable for?

IUI is recommended only if the woman has at least one healthy fallopian tube, confirmed laparoscopically or demonstrated by hysterosalpingogram (the tubal dye study), and if the man’s semen analysis is normal or near normal. It may be useful for women who have cervical mucus hostility and in some cases of unexplained infertility.

What does IUI involve?

1- Ovulation induction
2- Monitoring follicles (where eggs grow) development using transvaginal ultrasound with or without hormonal measurements till eggs are mature.
3- Triggering ovulation
4- Semen processing & insemination

On the day of the planned insemination, the husband provides a semen sample. A concentrated preparation of motile sperm is extracted from the semen sample in the laboratory. The sperm preparation is placed into the uterine cavity by means of a fine catheter inserted through the cervix. In general IUI is a painless procedure, which takes only a few minutes.

Process of semen processing

There are several techniques available for preparing the sperm for IUI. All of the techniques involve separating sperms from seminal fluid. It is not possible to inject semen directly into the uterus because of chemicals in the fluid that can cause extremely painful uterine contractions. At Ganin, we primarily use a certain method that separate good fertile sperms from the rest of semen.

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Dr. Andrew Cruize, MD

Dr. Andrew Cruize, MD

Reproductive endocrinology and infertility
Dr. Anne William, MD

Dr. Anne William, MD

Reproductive endocrinology and infertility
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